Table 3.
Assay of GEM, and RSV raw materials and their combined synthetic tablets using the proposed method and comparison with the reported spectrophotometric method.
| Parameters | Proposed method | Reference method | |||
|---|---|---|---|---|---|
| GEM | RSV | GEM | RSV | ||
| Raw materials | Mean % recovery ± SDa | 100.66 ± 0.24 | 99.51 ± 0.38 | 100.28 ± 0.53 | 99.26 ± 0.79 |
| RSD% | 0.24 | 0.38 | 0.53 | 0.80 | |
| F-testb | 0.21 | 0.23 | |||
| t-testb | 1.47 | 0.64 | |||
| Synthetic Zemiro tablets | Mean % recovery ± SDa | 98.83 ± 0.86 | 100.19 ± 0.64 | 99.77 ± 0.75 | 99.39 ± 0.94 |
| RSD% | 0.87 | 0.64 | 0.75 | 0.95 | |
| F-testb | 1.25 | 0.47 | |||
| t-testb | 0.51 | 1.58 | |||
aMean% recovery ± SD of five determinations.
bThe tabulated values of F and t, at p = 0.05, are 6.39 and 1.86, respectively.