TABLE 4.

The association of TMAO and KYN metabolites and odds of MetS and its components.

Variables		High levels TMAO (≥30.39 pg/mL)				High levels KYN (≥297.18 nmol/L)
		β	OR	95%CI	P-value	β	OR	95%CI	P-value
Mets+	Crude	0.71	2.03	1.23–3.37	0.006	0.28	1.33	0.81–2.19	0.25
	Adjusted	0.86	2.37	1.31–4.28	0.004	0.39	1.48	0.83–2.63	0.04
Hypertriglyceridemia	Crude	0.51	1.67	1.01–2.75	0.04	−0.03	0.96	0.59–1.59	0.89
	Adjusted	0.68	1.99	1.11–3.54	0.01	−0.03	0.96	0.54–1.69	0.89
Hyperglycemia	Crude	0.16	1.17	0.64–2.13	0.60	0.32	1.72	0.97–2.52	0.28
	Adjusted	0.05	1.05	0.52–2.09	0.88	0.28	1.75	1.05–3.61	0.42
Abdominal obesity	Crude	0.48	1.63	0.98–2.69	0.19	0.51	1.68	1.01–2.77	0.06
	Adjusted	0.42	1.52	0.80–2.87	0.05	0.59	1.81	1.05–3.44	0.04
Hypertension	Crude	−0.22	0.80	0.40–1.58	0.52	0.11	1.12	0.57–2.21	0.73
	Adjusted	−0.08	0.91	0.43–1.94	0.82	0.22	1.25	0.59–2.62	0.54
Low HDL	Crude	0.65	1.92	1.09–3.38	0.02	−0.11	0.88	0.51–1.54	0.67
	Adjusted	0.67	1.95	1.04–4.06	0.05	−0.25	0.77	0.38–1.57	0.47

TMAO, trimethylamine N-Oxide; KYN, kynurenine; MetS, metabolic syndrome. P-values < 0.05 were considered significant, bolding in Table. P-value for adjustment model, based on age, energy intake, physical activity, BMI and sex. TMAO<30.39 pg/mL, KYN<297.18 nmol/L, MetS-, normal values of TG, FBS, WC, BP and HDL were the reference group.