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. 2024 Feb 5;7(4):e202302353. doi: 10.26508/lsa.202302353

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© 2024 Yin et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure S1. — (A) Deep-sequencing reads distribution for MCF10A cell with radiation treatment samples. The distributions of each sgRNA are presented. (B) Precision-recall plots of essential genes identified from these screens. The dashed line marks the 5% FDR. (C) Changes in essential and nonessential genes during the CRISPR screens. Comparing time point 12 (T12A and T12B, two technical replicates) with 5 (T5) and time point 19 (T19A and T19B, two technical replicates) with 5 (T5), sgRNAs targeting essential genes changed dramatically, but no change in sgRNAs targeting nonessential genes was observed.