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. 2023 Dec 28;28(3):e18086. doi: 10.1111/jcmm.18086

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© 2023 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Transforming growth factor α (TGFA) levels are associated with tumour immune cell infiltration. (A) Infiltration levels of 24 types of immune cells in samples with different TGFA expression levels. (B) Analysis of the correlation between TGFA and 24 kinds of immune cell infiltration levels. (C) Thermogram of correlation between TGFA expression and surface labelled proteins of various immune cells:CR2 (B cells), CD8A(cytotoxic cells), SIGLEC8(eosinophils), CD1A (iDCs), TPSAB1(mast cells), B3GAT1 (NK cells), and IL3RA (pDCs), CD3G (T cells), CD3D (T cells), CD3E (T cells), CD4 (T helper cells), PTPRC (Tcm), CXCR5 (Tfh), IL17A (Th17), GATA3 (Th2) and FOXP3 (Treg). (D–F) Correlation analysis of TGFA with DSG2, RAB31 and CLCA2 expression levels. Significance identifier: ns (no significance), p ≥ 0.05; *p < 0.05; **p < 0.01; ***p < 0.001.