Table 2.
Treatment Received by Patients With Lung Cancer Diagnosed Through Four Different Pathways
| Treatment Characteristics | LDCT |
LNP |
MDC |
Non-Program |
p-Value |
|---|---|---|---|---|---|
| N = 237 | N = 1165 | N = 1140 | N = 9606 | ||
| Modality | <0.0001 | ||||
| Surgery only | 69 (29.1) | 281 (24.1) | 204 (17.9) | 1092 (11.4) | |
| Any surgery | 111 (46.8) | 410 (35.2) | 446 (39.1) | 1660 (17.3) | |
| Any curative-intent treatment: surgery or definitive radiation | 158 (66.7) | 702 (60.3) | 643 (56.4) | 4831 (50.3) | |
| Systemic treatment | 23 (9.7) | 146 (12.5) | 189 (16.6) | 1886(19.6) | |
| Radiation only | 34 (14.4) | 167 (14.3) | 97 (8.5) | 1202 (12.5) | |
| Radiation with other | 55 (23.2) | 251 (21.6) | 334 (29.3) | 2519 (26.2) | |
| No treatment | 14 (5.9) | 190 (16.3) | 74 (6.5) | 2338 (24.3) |
| Adjuvant therapy for recipients of surgery | |||||
|---|---|---|---|---|---|
| Neoadjuvant | na = 111 | na = 410 | na = 446 | na = 1660 | <0.001 |
| No | 109 (98.2) | 394 (96.1) | 391 (87.7) | 1558 (93.9) | |
| Yes | 2 (1.8) | 16 (3.9) | 55 (12.3) | 102 (6.1) | |
| Adjuvant | <0.001 | ||||
| No | 75 (67.6) | 307 (74.9) | 268 (60.1) | 1219 (73.4) | |
| Yes | 36 (32.4) | 103 (25.1) | 178 (39.9) | 441 (26.6) | |
| Both | 0 | 4 (1.0) | 9 (2.0) | 14 (0.84) | 0.038 |
| Pathologic tumor size (mm) | 0.004 | ||||
| Mean (SD) | 24.1 (14.5) | 24.8 (13.9) | 31.26 (18.3) | 26.8 (16.4) | |
| Median (Q1–Q3) | 20 (15–27) | 22 (15–30) | 27 (18–40.8) | 22 (15–33) | |
| (Min–Max) | (8–77) | (2–80) | (0–90) | (0–91) | |
| Aggregate pathologic stage | <0.001 | ||||
| Stage I | 77 (69.4) | 262 (63.9) | 183 (41.0) | 733 (44.2) | |
| Stage II | 10 (9.0) | 49 (11.9) | 63 (14.1) | 184 (11.1) | |
| Stage III | 10 (9.0) | 31 (7.6) | 34 (7.6) | 125 (7.5) | |
| Stage IV | 1 (0.9) | 12 (2.9) | 38 (8.6) | 67 (4.0) | |
| Not Reported | 13 (11.7) | 56 (13.7) | 128 (28.7) | 551 (33.2) | |
| Combined pathologic stage | <0.001 | ||||
| Early stage | 87 (78.4) | 311 (75.8) | 246 (55.2) | 917 (55.2) | |
| Advanced stage | 11 (9.9) | 43 (10.5) | 72 (16.1) | 192 (11.6) | |
| Not reported | 13 (11.7) | 56 (13.7) | 128 (28.7) | 551 (33.2) | |
Modality percentages are used the column head as the denominator; adjuvant therapy percentage used the number of patients underwent surgery; p-value of the modality is computed with four exclusive groups: surgery only, systemic therapy, radiation only and no treatment.
LDCT, lung cancer screening program; LNP, Lung Nodule Program; Max, maximum; MDC, multidisciplinary care program; Min, minimum; Q, quartile.
a
Denominator for all column percentages (numbers in parentheses) is patients within column category who had surgery.