Table 2.
Quality of life studies in chronic kidney disease patients on hemodialysis.
| Study (Type) | Study objective | Patient population | Inclusion/ Exclusion criteria |
Tools used/ Administration |
Results | QoL domains |
|---|---|---|---|---|---|---|
| Picariello et al. (2020) (Picariello et al., 2018, Picariello et al., 2021) RCT |
Evaluation of the applicability of cognitive behavioral therapy (CBT)-based intervention efficacy trial. |
Adult patients undergoing In-center hemodialysis who meet clinical levels of fatigue. (n = 40) |
Inclusion: Age > 18 years; confirmed ESKD diagnosis; fatigue levels exceed 18 on the CFQ; receiving in-center HD; length of time on dialysis > 90 days Exclusion: The presence of any known cognitive impairments ; have a severe mental health disorder; currently receiving psychotherapy; failing on dialysis and approaching the end of life; have a CFQ score below the cut-off at the Pre-randomization assessment |
CFQ, WSAS, IPAQ-SF | Results showed that a cognitive-behavioral therapy (CBT) based intervention for fatigue in hemodialysis appeared necessary and beneficial. The study found moderate to significant treatment effects in favor of the intervention, specifically on fatigue severity, fatigue-related functional impairment, depression, and anxiety. However, there was no significant improvement in sleep quality. | Physical Social Psychological |
| Suhardjono et al. (2019) (Suhardjono et al., 2019) RCT |
Evaluation of the role of intradialytic exercise on physical capacity, inflammation, and nutritional status of dialysis patients. |
N = 120, 18 age or older; on maintenance dialysis for at least 3 months |
Inclusion: dialysis patients aged over 18 years who had undergone routine dialysis for over three months/ Exclusion: traveling on dialysis, being hospitalized for any reason within the past three months, having arrhythmias, being on dialysis for less than 2‐week intervals, having a limited range of motion of extremities, being immobilized |
IPAQ Self-administered |
The study found a notable improvement in the lower extremity strength and physical component score (PCS) of the KDQOL-SF™ tool among patients who underwent aerobic training and combination exercise, as compared to those in the control group. | Physical |
| Matsufuji et al.(2014) (Matsufuji et al., 2015) RCT |
Evaluation of the effect of chair stand exercise on ADL of hemodialysis patients. | N = 27; outpatients on hemodialysis; age ˃ 60 years |
Inclusion: on hemodialysis; age ˃ 60 years; ambulatory Exclusion: symptomatic ischemic heart disease; symptomatic peripheral artery disease; arthritis; history of stroke with severe paralysis; chronic obstructive pulmonary disease; pregnancy. |
(FIM) HCP-administered |
Significant improvement in the FIM subscales related to mobility and locomotion. |
Physical; psychological; social |
| Sihombing et al. (2016) (J.S. et al., 2017) Multicenter prospective study |
Evaluation of the effect of erythropoietin on the QoL of CKD patients. | CKD patients with routine hemodialysis |
Inclusion Criteria: CKD patients with routine hemodialysis for at least three months, aged 20–80 years, use EPO to treat their anemia. Exclusion: Kidney transplant; diagnosed with cancer. |
FACIT-F | Erythropoietin could positively impact the quality of life (QOL) of chronic kidney disease (CKD) patients undergoing routine hemodialysis. | Physical |
| Zhang et al. (2020) (Zhang et al., 2020) Systematic Review and meta-analysis |
Evaluation of the therapeutic efficacy of exercise for patients undergoing hemodialysis on fatigue and HRQoL. |
Patients with ESRD undergoing hemodialysis |
Inclusion Criteria: Patients with ESRD undergoing hemodialysis who were diagnosed using the Kidney Disease Improving Global Outcomes. Exclusion: None. |
PFS, FACIT-F, CFQ) |
Results are not reported yet. | Physical |