Table 1.
Brain morphological alterations in post-traumatic stress disorder.
| Study | Participants | Analysis | Brain Results | |
|---|---|---|---|---|
| Nardo et al., 2010 [167] | 21 PTSD/22 TC | Whole-brain VBM | ↓ | GMC - PCG, Precuneus Cortex, Lingual Gyrus, Parahippocampus |
| Zhang et al., 2011 [169] | 10 PTSD/10 TC | Whole-brain VBM | ↓ | GMV - Hippocampus, Parahippocampus, Calcarine Cortex |
| Baldaçara et al., 2012 [172] | 42 PTSD/42 TC | ROI VBM: Cerebellum | ↓ | GMV - Cerebellum |
| Tavanti et al., 2012 [165] | 25 PTSD/25 HC | Whole-brain VBM | ↓ | GMV - Frontal Pole, SFG, MFG, IFG-Pars Triangularis, Paracingulate Gyrus, Precentral Gyrus, Postcentral Gyrus, PCG, Intracalcarine Cortex, Lateral Occipital Cortex, Lingual Gyrus, Occipital Fusiform Gyrus, Occipital Pole, Precuneus Cortex, Supracalcarine Cortex, Temporal Occipital Fusiform Cortex, ITG |
| Tan et al., 2013 [168] | 12 PTSD/14 TC | Whole-brain VBM | ↓ | GMV - Superior Parietal Lobule, SFG |
| Bossini et al., 2017 [166] | 19 PTSD/19 HC | Whole-brain VBM |
↓
↑ |
GMV - Parahippocampus, SMA, Lingual Gyrus, SFG GMV - Angular Gyrus, Inferior Parietal Lobe, ITG |
Abbreviations: GMC, Gray Matter Concentration; GMV, Gray Matter Volume; HC, Healthy Controls; IFG, Inferior Frontal Gyrus; ITG, Inferior Temporal Gyrus; MFG, Middle Frontal Gyrus; PCG, Posterior Cingulate Gyrus; PTSD, Post-Traumatic Stress Disorder; ROI, Region-of-Interest; SFG, Superior Frontal Gyrus; SMA, Supplementary Motor Area; TC, Traumatized Controls; VMB, Voxel-Based Morphometry.
↓ Lower regional GMV/GMC in patients.
↑ Greater regional GMV/GMC in patients.