TEM of HMDM and J774 cells infected with hemolysin-positive and -negative EAggEC and CDEC strains. (A and B) HMDM infected with Hly+ EAggEC shown in a state of necrosis; (C) HMDM infected with Hly− EAggEC or CDEC strains; (D and E) J774 cells infected with Hly+ CDEC strain 55-3; (F) J774 cells infected with Hly− CDEC strain 55-3. Bar markers: 2 μm (A and C) and 1 μm (B, D, E, and F). b, bacteria; n, nucleus; and sn, swollen nucleus; an, apoptotic nucleus.