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. 2023 Nov 6;22(4):636–735. doi: 10.2174/1570159X22666231027111147

Table 5.

Overview of clinical studies of LSD for the treatment of PTSD.

Study First
Author, Year
Sample Size Method Measures Study Type Effect Statistical Outcome
Oehen and Gasser, 2022 [623] n = 50 Characterization of a model utilizing MDMA- and LSD- (sequentially) assisted group / individual psychotherapy for patients with various trauma-related disorders including complex PTSD (c-PTSD) in a clinical practice in Switzerland (PAP) Outcomes assessed via clinical judgment; structured assessments not utilized regularly N/A Majority of participants improved, as assessed by clinical judgment. N/A

Abbreviations: c-PTSD: Complex post-traumatic stress disorder, LSD: Lysergic acid diethylamide, MDMA: 3,4-methylenedioxy-methamphetamine, PAP: Psychedelic-Assisted Psychotherapy, PTSD: Post-traumatic stress disorder.