Figure A1.

Suppressed motifs and their impact on the propagation of perturbations. (A) Set of suppressed motifs. To improve the readability of this visualization, the set of suppressed motifs was approximately clustered by structural similarity. Each blue circle represents a cluster. The line between motifs inside a cluster shows how motifs in the cluster are related. The beige circle represents the global structure of the motifs inside the blue cluster. (B) Small perturbations propagate more in evolved networks than in random and suppressed motif networks. We sample the average distance between two states which initially differs only by one component after 3 updates (triangle) and after 510 updates (square).