Table 2.

Odds ratios for 30-day postoperative complications among patients with gallbladder cancer who underwent neoadjuvant chemotherapy (n = 411¹)

Primary outcome2	Odds ratio	95% confidence Interval	P value
Post-operative bile leak	0.69	0.16, 2.10	0.55
Secondary outcomes3
Required blood transfusion	1.80	0.83, 3.61	0.11
On the ventilator > 48 h	3.96	0.54, 20.83	0.12
Length of ICU stay	1.09	0.97, 1.22	0.12
Readmission	0.68	0.23, 1.64	0.44
Superficial incisional wound infection	0.58	0.03, 3.02	0.61
Organ space wound infection	0.63	0.18, 1.63	0.39
Required secondary intervention	0.41	0.10, 1.17	0.15
Conversion rate to open	1.67	0.47, 4.67	0.37
Need for biliary reconstruction	1.15	0.54, 2.27	0.70

¹Patients with missing data were omitted from analysis.

²Adjusted odds ratio with the model including the primary predictor (neoadjuvant chemotherapy) and potential confounders (race, ethnicity, placement of a biliary stent, and preoperative bilirubin).

³Unadjusted odds ratios.

Comparison group is patients having surgery for gallbladder cancer without neoadjuvant chemotherapy. ICU: Intensive care unit.