. 2012 Jul 19;27(5):321–330. doi: 10.1177/1533317512452035

Table 3.

Cutoff, Sensitivity, Specificity, Likelihood Ratio, Area Under Curve (AUC), Standard Error and Associated Probability for Both VReoT Scores (ie, Sum of Scores of All Subtests), and the Shortest Best Subtest Arrangements (ie, knew that A = Layout Only, B = Layout and Positional Landmark, C = Layout and Directional Landmark, D = Positional Landmark Only, E = Directional Landmark Only), for Each Group Comparison. Z Scores and Associated Probabilities Were Calculated to Compare the AUCs for Each VReoT Score and the Shortest Best Subtest Arrangements, Following Hanley and McNeil's formula.⁵⁹ $z = \frac{A_{1} - A_{2}}{\sqrt{S E_{1}^{2} + S E_{2}^{2} - 2 r S E_{1} S E_{2}}}$ .

		Cutoff	Sensibility, %	Specificity, %	Likelihood ratio	AUC	SE	P	z	P
aMCI vs HC	VReoT score	>7	80.4	94.3	14.2	0.902	0.032	<.001	0.81	NS
aMCI vs HC	Sum of D and E	>2	84.3	81.1	4.5	0.883	0.035	<.001
aMCIsd vs HC	VReoT score	>7	78.6	94.3	13.9	0.877	0.048	<.001	0.22	NS
aMCIsd vs HC	Sum of D and E	>2	82.1	81.1	4.4	0.870	0.048	<.001
aMCImd vs HC	VReoT score	>7	82.6	94.3	14.6	0.931	0.038	<.001	1.10	NS
aMCImd vs HC	Sum of A, C and E	>5	78.3	86.8	5.9	0.907	0.041	<.001
aMCImd vs aMCIsd	VReoT score	>7	82.6	21.4	1.0	0.609	0.081	NS	−1.12	NS
aMCImd vs aMCIsd	Sum of B and D	>3	78.3	42.9	1.4	0.700	0.075	<.05

Abbreviations: aMCI, amnestic mild cognitive impairment; aMCIsd, amnestic MCI single domain; aMCImd, amnestic MCI multiple domain; SE, standard error; AUC, area under the curve; HC, healthy control; VReoT, virtual reorientation test.