Table2.

Pooled Data Analysis of Clusterin-SNP rs11136000

Study	Number		MAF		HWE		Association Study
	Cases	Controls	Cases	Controls	Cases	Controls	OR (95%, CI)	P Value
Yu et al	324	388	0.17	0.19	0.01	0.422	0.89 (0.62-1.17) a	.492
							0.20 (0.04-0.88) b	.03 c
							0.83 (0.64-1.10) d	.21
Chen et al	451	338	0.21	0.23	0.12	0.17	0.93 (0.70-1.25) a	.66
							0.45 (0.23-0.87) b	.02 d
							0.86 (0.68-1.09) d	.22
This study	127	143	0.21	0.24	0.43	0.15	0.72 (0.44-1.18) a	.20
							1.61 (0.50-5.21) b	.56
							0.85 (0.56-1.27) d	.47
Pooled							0.88 (0.72-1.07) a	.187 e
							0.53 (0.31-0.91) b	.020c,f
							0.85 (0.72-1.00) d	.048c,g

Abbreviations: MAF, minor allele frequency; HWF, Hardy-Weinberg equilibrium; OR, odds ratio; CI, confidence interval; df, degrees of freedom.

^a Dominant model: TT + TC versus CC.

^b Recessive model: TT versus TC + CC.

^c P < .05

^d Allele frequency: T versus C.

^e Heterogeneity: Q = 0.812, df = 2, P = .666, fixed-effect model was adopted, test for overall effect: z = −1.318

^f Heterogeneity: Q = 5.383, df = 2, P = .068, fixed-effect model was adopted, test for overall effect: z = −2.323

^g Heterogeneity: Q = 0.022, df = 2, P = .989, fixed-effect model was adopted, test for overall effect: z = −1.977