Table 3.
APOE genotypes | Age, y | Age at onset | Education | MMSE | Months follow-up | Family history of dementia |
---|---|---|---|---|---|---|
2/3 (n = 5) | 65.4 ± 6.1 | 62.6 ± 8.0 | 12.0 ± 0.0 | 21.5 ± 5.7 | 15 (1, 72) | 100.0% |
3/3 (n = 21) | 61.4 ± 9.2 | 59.4 ± 9.09 | 14.5 ± 2.9 | 22.7 ± 4.5 | 12 (1, 72) | 42.1% |
2/4 (n = 2) | 54.0 ± 1.4 | 52.5 ± 2.1 | 12.0 (n = 1) | 25.0 ± 2.8 | 21 (18, 24) | 0.0% |
3/4 (n = 37) | 67.1 ± 10.7 | 64.5 ± 11.5 | 14.9 ± 3.2 | 21.9 ± 6.1 | 12 (2, 60) | 67.6% |
4/4 (n = 24) | 65.5 ± 7.0 | 62.1 ± 7.5 | 14.5 ± 2.9 | 20.1 ± 6.6 | 18 (1, 72) | 54.2% |
P value of ∊4 versus non-∊4 carriers | .07 | .16 | .56 | .46 | .48 | .62 |
Abbreviations: APOE, apolipoprotein E; MMSE, Mini-Mental State Examination; SD, standard deviation.
a Values are mean ± SD except month follow-up expressed as a median (minimum and maximum).