Table 2.
The Results of Each Item
Caregivers a | Patients b | Disc c | Pred. C d | Pred. P e | |||
---|---|---|---|---|---|---|---|
CDR | Mean ± SD | Mean ± SD | P value | ||||
Intellectual functioning domain | |||||||
1 | Problems with remembering dates | 0.5 | 1.17 ± 0.83 g | 0.92 ± 0.67 g | .429 | ||
1 | 1.91 ± 0.79 h | 1.30 ± 0.76 h | .016 f | ||||
2 | 2.61 ± 0.50 h | 1.11 ± 0.76 h | <.001 h | ||||
2 | Problems with orientation in new places | 0.5 | 0.42 ± 0.51 f | 0.25 ± 0.45 | .166 | ||
1 | 1.17 ± 1.03 h | 0.74 ± 0.92 g | .047 f | ||||
2 | 1.78 ± 1.00 h | 0.78 ± 0.73 h | .004 g | ||||
3 | Problems with remembering telephone call | 0.5 | 0.50 ± 0.67 f | 0.33 ± 0.49 f | .551 | ||
1 | 1.43 ± 0.79 h | 0.65 ± 0.71 h | <.001 h | ||||
2 | 2.06 ± 1.11 h | 0.17 ± 0.38 | <.001 h | ||||
4 | Problems with understanding conversations | 0.5 | 0.58 ± 0.67 f | 0.33 ± 0.49 f | .389 | ||
1 | 1.13 ± .63 h | 0.52 ± 0.59 h | .002 g | ||||
2 | 1.78 ± 0.88 h | 0.11 ± 0.47 | <.001 h | ||||
5 | Problems with signing your name | 0.5 | 0.08 ± 0.29 | 0.00 ± 0.00 | .339 | ||
1 | 0.22 ± 0.42 f | 0.17 ± 0.49 | .747 | ||||
2 | 1.33 ± 1.14 h | 0.00 ± 0.00 | <.001 h | ||||
6 | Problems with understanding the newspaper | 0.5 | 0.25 ± 0.45 | 0.58 ± 0.67 f | .166 | ||
1 | 1.00 ± 0.95 h | 0.43 ± 0.51 h | .020 f | .221 f | |||
2 | 1.94 ± 0.94 h | 0.11 ± 0.32 | <.001 h | ||||
7 | Problems with keeping belongings in order | 0.5 | 0.75 ± 0.97 f | 0.58 ± 0.79 f | .551 | ||
1 | 1.61 ± 0.99 h | 0.43 ± 0.66 g | <.001 h | ||||
2 | 2.44 ± 0.70 h | 0.22 ± 0.43 f | <.001 h | ||||
8 | Problems with remembering where things were left | 0.5 | 1.50 ± 0.80 h | 0.83 ± 0.39 h | .005 g | .555 f | |
1 | 1.78 ± 0.80 h | 1.04 ± 0.64 h | .001 g | .352 g | |||
2 | 2.33 ± 0.77 h | 0.83 ± 0.51 h | <.001 h | ||||
9 | Problems with writing | 0.5 | 0.67 ± 0.89 f | 0.33 ± 0.49 f | .166 | ||
1 | 0.96 ± 0.71 h | 0.52 ± 0.79 g | .022 f | .934 h | .533 h | ||
2 | 2.17 ± 0.86 h | 0.28 ± 0.75 | <.001 h | ||||
10 | Problems with handling money | 0.5 | 0.50 ± 1.00 | 0.25 ± 0.62 | .082 | ||
1 | 1.04 ± 1.07 h | 0.35 ± 0.71 f | .015 f | ||||
2 | 2.06 ± 1.00 h | 0.11 ± 0.47 | <.001 h | ||||
11 | Problems with orientation in your neighborhood | 0.5 | 0.33 ± 0.89 | 0.08 ± 0.29 | .389 | ||
1 | 0.65 ± 0.83 g | 0.30 ± 0.56 f | .103 | ||||
2 | 1.39 ± 1.14 h | 0.11 ± 0.32 | <.001 h | ||||
12 | Problems with remembering appointments | 0.5 | 0.67 ± 0.89 f | 0.50 ± 0.52 g | .504 | .766 g | |
1 | 1.78 ± 0.95 h | 0.78 ± 0.67 h | <.001 h | .388 g | |||
2 | 1.94 ± 0.80 h | 0.56 ± 0.62 g | <.001 h | ||||
13 | Problems with practicing favorite hobbies | 0.5 | 0.17 ± 0.39 | 0.25 ± 0.45 | .674 | ||
1 | 0.83 ± 0.94 h | 0.39 ± 0.72 f | .038 f | −.309 f | |||
2 | 1.67 ± 0.97 h | 0.28 ± 0.75 | <.001 h | ||||
14 | Problems with communicating with people | 0.5 | 0.08 ± 0.29 | 0.25 ± 0.45 | .339 | ||
1 | 0.74 ± 0.69 h | 0.35 ± 0.49 g | .025 f | ||||
2 | 1.39 ± 0.92 h | 0.00 ± 0.00 | <.001 h | −.471 h | |||
15 | Problems with mental calculations | 0.5 | 0.42 ± 0.67 | 0.83 ± 0.39 h | .054 | ||
1 | 1.17 ± 0.89 h | 1.22 ± 0.80 h | .852 | .322 g | |||
2 | 1.83 ± 1.10 h | 0.83 ± 1.15 g | .022 f | .523 g | |||
16 | Problems with remembering shopping lists | 0.5 | 0.75 ± 0.87 f | 0.58 ± 0.51 g | .638 | ||
1 | 1.65 ± 0.93 h | 0.74 ± 0.81 h | <.001 h | ||||
2 | 2.22 ± 0.81 h | 0.50 ± 0.71 g | <.001 h | ||||
17 | Problems with bladder control | 0.5 | 0.17 ± 0.58 | 0.00 ± 0.00 | .339 | ||
1 | 0.39 ± 0.84 f | 0.13 ± 0.34 | .186 | ||||
2 | 1.00 ± 1.03 g | 0.00 ± 0.00 | .001 g | .382 g | |||
18 | Problems with understanding the plot of a movie | 0.5 | 0.25 ± 0.45 | 0.42 ± 0.51 f | .438 | ||
1 | 1.09 ± 0.67 h | 0.52 ± 0.51 h | .006 g | ||||
2 | 1.67 ± 1.03 h | 0.11 ± 0.32 | <.001 h | ||||
19 | Problems with orientation in the house | 0.5 | 0.00 ± 0.00 | 0.00 ± 0.00 | – | ||
1 | 0.13 ± 0.34 | 0.00 ± 0.00 | .083 | ||||
2 | 0.94 ± 1.11 g | 0.00 ± 0.00 | .002 g | ||||
20 | Problems with doing home activities | 0.5 | 0.92 ± 1.16 f | 0.42 ± 0.67 | .166 | ||
1 | 1.09 ± 1.04 h | 0.22 ± 0.42 f | .001 g | ||||
2 | 2.06 ± 0.94 h | 0.11 ± 0.32 | <.001 h | ||||
21 | Problems with feeding oneself | 0.5 | 0.42 ± 1.00 | 0.00 ± 0.00 | .175 | ||
1 | 0.17 ± 0.49 | 0.04 ± 0.21 | .266 | ||||
2 | 1.00 ± 1.14 g | 0.06 ± 0.24 | .004 g | .490 h | |||
22 | Problems with doing clerical work | 0.5 | 0.92 ± 1.16 f | 0.75 ± 0.97 f | .504 | .439 f | |
1 | 1.52 ± 1.08 h | 0.74 ± 1.10 g | .002 g | ||||
2 | 2.33 ± 0.84 h | 0.94 ± 1.35 g | .002 g | .574 h | .439 f | ||
Sum | 0.5 | 11.50 ± 10.48 h | 8.50 ± 4.87 h | 0.389 | |||
1 | 23.48 ± 9.68 h | 11.61 ± 6.66 h | <.001 h | ||||
2 | 39.94 ± 14.65 h | 7.22 ± 4.14 h | <.001 h | ||||
Mood and behavior domains | |||||||
23 | More rigid and inflexible about decisions | 0.5 | 0.75 ± 0.87 f | 0.58 ± 0.90 f | .339 | ||
1 | 1.57 ± 0.90 h | 0.61 ± 0.72 g | <.001 h | ||||
2 | 2.06 ± 0.80 h | 0.94 ± 1.21 g | .003 g | ||||
24 | More egotistical and self-centered | 0.5 | 0.92 ± 0.90 g | 0.58 ± 0.67 f | .266 | ||
1 | 1.39 ± 0.94 h | 0.26 ± 0.45 f | <.001 h | ||||
2 | 1.56 ± 0.86 h | 0.67 ± 0.97 f | <.001 h | ||||
25 | More irritable | 0.5 | 0.50 ± 0.67 f | 0.58 ± 0.51 g | .723 | ||
1 | 0.96 ± 0.93 h | 0.39 ± 0.58 g | .020 f | ||||
2 | 1.22 ± 0.88 h | 0.83 ± 1.04 g | .149 | ||||
26 | More frequent crying episodes | 0.5 | 0.08 ± 0.29 | 0.42 ± 0.51 f | .104 | ||
1 | 0.48 ± 0.79 g | 0.43 ± 0.66 g | .770 | ||||
2 | 0.67 ± 0.84 g | 0.83 ± 0.99 g | .636 | ||||
27 | Laughing inappropriately | 0.5 | 0.08 ± 0.29 | 0.17 ± 0.39 | .586 | ||
1 | 0.17 ± 0.39 f | 0.22 ± 0.52 | .770 | ||||
2 | 0.39 ± 0.61 f | 0.06 ± 0.24 | .029 f | ||||
28 | Increased sexual interest | 0.5 | 0.00 ± 0.00 | 0.17 ± 0.39 | .166 | ||
1 | 0.13 ± 0.34 | 0.09 ± 0.29 | .665 | ||||
2 | 0.11 ± 0.32 | 0.06 ± 0.24 | .579 | ||||
29 | Less interest in favorite activities | 0.5 | 0.50 ± 0.67 f | .42 ± 0.51 f | .723 | ||
1 | 1.00 ± 0.85 h | .65 ± 0.93 g | .088 | ||||
2 | 1.61 ± .92 h | .61 ± 1.04 f | .001 g | ||||
30 | More depressed | 0.5 | .83 ± 0.83 g | .42 ± 0.67 | .096 | ||
1 | 1.13 ± 0.87 h | 0.70 ± 0.76 h | .038 f | ||||
2 | 1.33 ± 0.69 h | .56 ± 0.92 f | .012 f | ||||
Sum | 0.5 | 3.67 ± 2.77 h | 3.33 ± 2.99 h | 0.768 | |||
1 | 6.83 ± 3.41 h | 3.35 ± 2.92 h | <.001 h | ||||
2 | 8.94 ± 2.60 h | 4.56 ± 4.00 h | <.001 h |
Abbreviation: SD, standard deviation; CDR, Clinical Dementia Rating scale.
a Scores of caregivers were analyzed by one-sample t test, and statistically significance was denoted.
b Scores of caregivers patients were analyzed by one-sample t test, and statistically significance was denoted.
c Discrepancy between caregivers’ and patients’ assessment, showing severity of anosognosia; discrepancy was evaluated by paired t test.
d Predictors of distress in caregivers were analyzed by multivariate regression model, and statistically significant standardized beta value was shown in the column.
e Predictors of distress in patients were analyzed by multivariate regression model, and statistically significant standardized beta value was shown in the column.
f P < .05.
g P < .01.
h P < .001.