Table 4.
Expression levels of SIRT-1, TGF-β, and miR-182 among healthy, FA, and BC study participants.
| Parameters | Healthy control | FA | BC | ||
|---|---|---|---|---|---|
| Mean ± SEM | Mean ± SEM | P | Mean ± SEM | P | |
| SIRT-1 (ng/mL) | 4.27 ± 0.066a | 4.66 ± 0.105b | .007 | 8.22 ± 0.080c | .001 |
| TGF-β (ng/mL) | 1.74 ± 0.034a | 6.26 ± 0.474b | .001 | 10.46 ± 0.352c | .001 |
| miR-182 | 0.97 ± 0.006a | 1.31 ± 0.034a | .556 | 6.13 ± 0.40b | .001 |
Abbreviations: BC, breast cancer; FA, fibroadenoma; miR-182, microRNA-182; SIRT-1, sirtuin 1; TGF-β, transforming growth factor-beta.
Data were expressed as mean ± SEM (standard error mean); according to the Tukey multiple range test, the different letters indicate statistical significance different means.