Table 3B:

Adjusted odds ratios comparing neonatal cytokine and chemokine concentrations in ASD (severe, mild to moderate symptoms), DD, and TD in one model, N=398^a

Cytokine or Chemokine	ASDsev vs. ASDmild			ASDsev vs. TD			ASDmild vs. TD
	OR	95% CI	P-value	OR	95% CI	P-value	OR	95% CI	P-value
CTACK	0.83	0.32, 2.12	0.70	0.38	0.49, 0.77	0.01	0.46	0.18, 1.15	0.10
MPIF-1	0.79	0.42, 1.49	0.46	0.89	0.56, 1.41	0.61	1.13	0.60, 2.10	0.71
MIF	1.53	0.64, 3.66	0.34	0.69	0.26, 1.80	0.44	0.45	0.15, 1.30	0.14
Cytokine or Chemokine	ASDsev vs. DD			ASDmild vs. DD			DD vs. TD
	OR	95% CI	P-value	OR	95% CI	P-value	OR	95% CI	P-value
CTACK	0.46	0.19, 1.11	0.08	0.55	0.19, 1.60	0.27	0.82	(0.35, 1.94)	0.65
MPIF-1	2.23	1.29, 3.84	0.004	2.83	1.42, 5.64	0.003	0.40	(0.24, 0.68)	0.001
MIF	1.44	0.65, 3.21	0.37	0.94	0.45, 1.98	0.88	0.49	(0.18, 1.34)	0.17

^aMultinomial logistic regression model was adjusted for maternal education, gestational age, child’s age at blood spot collection, and years from blood spot collection to elution; cytokines/chemokines were ln-transformed and normalized for total protein (pg/mg total protein); OR represents the fold change in the odds of having one diagnosis relative to another diagnosis or no diagnosis for every 1-unit increase in the ln-transformed cytokine/chemokine (or for every e-fold increase in cytokine/chemokine levels); 398 participants comprised the following groups: 121 ASD-severe, 50 ASD-mild, 69 DD and 158 TD; OR = adjusted odds ratio, CI = confidence interval