Figure 6.

Correlation analysis between nucleophosmin/nucleoplasmin 3 expression level and immune cell infiltration. (A–J) Correlative analysis between NPM3 expression level and the infiltration of B cells, CD4⁺T cells, CD8⁺ T cells, Tregs, mast cells, cancer-associated fibroblasts, MDSCs, monocytes, macrophages, and DCs using TIMER, CIBERSORT, CIBERSORT-ABS, EPIC, MCPCOUNTER, QUANTISEQ, and XCELL algorithms. Correlations with P values < 0.05 are considered statistically significant and are indicated by black rectangles, and statistically insignificant correlation values are marked by crosses. Red indicates a positive correlation (0–1), while blue indicates a negative correlation (-1-0). ACC: Adrenocortical carcinoma; BLCA: Bladder urothelial carcinoma; BRCA: Breast invasive carcinoma; ccRCC: Clear cell renal cell carcinoma; CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma; CHOL: Cholangiocarcinoma; COAD: Colon adenocarcinoma; DC: Dendritic cell; DLBCL: Lymphoid neoplasm diffuse large B-cell lymphoma; ESCA: Esophageal carcinoma; GBM: Glioblastoma multiforme; HNSC: Head and neck squamous cell carcinoma; KICH: Kidney chromophobe; KIRC: Kidney renal clear cell carcinoma; KIRP: Kidney renal papillary cell carcinoma; LAML: Acute myeloid leukemia; LGG: Lower grade glioma; LIHC: Liver hepatocellular carcinoma; LUAD: Lung adenocarcinoma; LUSC: Lung squamous cell carcinoma; MECO: Mesothelioma; MDSC: Myeloid-derived suppressor cell; NPM3: Nucleophosmin/nucleoplasmin 3; OV: Ovarian serous cystadenocarcinoma; PAAD: Pancreatic adenocarcinoma; PCPG: Pheochromocytoma and paraganglioma; PRAD: Prostate adenocarcinoma; READ: Rectum adenocarcinoma; SARC: Sarcoma; SKCM: Skin cutaneous melanoma; STAD: Stomach adenocarcinoma; TGCT: Testicular germ cell tumors; THCA: Thyroid carcinoma; THYM: Thymoma; TIMER: Tumor immune estimation resource; UCEC: Uterine corpus endometrial carcinoma; UCS: Uterine Carcinosarcoma; UVM: Uveal melanoma.