Table 2A.

Area of Preserved EZ/IZ in mm² and Correlation Between RMDA and EZ/IZ Areas in the Entire Grid, Central Subfield, and Inner and Outer Rings of the ETDRS Grid in all Eyes and Subdivided by AREDS Categories (Normal, Early AMD, and Intermediate AMD Eyes)

	Correlation of RMDA at 5 Degrees With Area of EZ and IZ
			Area (mm2)			Correlation
Layer	ETDRS Subfield	AREDS Category	Mean	Std Dev	P Value	Correlation coefficient (r)	P Value
Ellipsoid zone (EZ)	Entire grid	All	28.149	0.068		−0.334	< 0 .0001
		Normal	28.270	0.023	<0.0001	−0.199	0.002
		Early	28.246	0.111		−0.272	0.001
		Intermediate	27.699	1.423		−0.268	0.007
	Central subfield	All	0.774	0.065		−0.217	<0.0001
		Normal	0.790	0.003	<0.0001	−0.055	0.401
		Early	0.787	0.014		−0.039	0.652
		Intermediate	0.752	0.088		−0.033	0.743
	Inner ring	All	6.232	0.281		−0.348	< 0 .0001
		Normal	6.280	0.011	<0.0001	−0.021	0.746
		Early	6.273	0.041		−0.117	0.175
		Intermediate	6.088	0.373		−0.227	0.023
	Outer ring	All	21.0893	1.058		−0.292	< 0 .0001
		Normal	21.2091	0.016	<0.0001	−0.291	< 0 .0001
		Early	21.1947	0.079		−0.322	< 0 .0001
		Intermediate	20.8628	1.128		−0.258	0.010
Interdigitation zone (IZ)	Entire grid	All	27.125	3.219		−0.591	< 0 .0001
		Normal	28.250	0.136	<0.0001	−0.442	< 0 .0001
		Early	27.909	0.777		−0.496	< 0 .0001
		Intermediate	23.223	5.538		−0.472	< 0 .0001
	Central subfield	All	0.707	0.192		−0.531	< 0 .0001
		Normal	0.789	0.011	<0.0001	−0.069	0.288
		Early	0.766	0.065		−0.257	0.001
		Intermediate	0.436	0.288		−0.288	0.004
	Inner ring	All	5.863	1.060		−0.584	< 0 .0001
		Normal	6.275	0.032	<0.0001	−0.107	0.101
		Early	6.173	0.235		−0.303	< 0 .0001
		Intermediate	4.397	1.646		−0.414	< 0 .0001
	Outer ring	All	20.555	2.190		−0.538	< 0 .0001
		Normal	21.195	0.122	<0.0001	−0.460	< 0 .0001
		Early	20.974	0.637		−0.460	< 0 .0001
		Intermediate	18.389	4.125		−0.450	< 0 .0001

P-values that indicate statistical significance (P values < 0.05) are in bold