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MRI shows Patient 2’s response to proton craniospinal irradiation and immune checkpoint inhibitor therapy. (A) 3- to 4-mm low-density subependymal nodules (arrows) were observed along the body of the left lateral ventricle and anterior horn of the left lateral ventricle, representing metastatic disease. (B) Resolution of low-density subependymal nodules (arrows) after treatment with ipilimumab and nivolumab, proton craniospinal irradiation, and nivolumab maintenance therapy.
