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. 2024 Feb 1;15(1):100879. doi: 10.1016/j.jaim.2023.100879

Table 2.

Contrasting ayurvedic and pharmacologic actions

Rasayana Ayurvedic Actions Pharmacologic Mechanisms of Actiona
Yashtimadhu Yashtimadhu is sweet with a bitter aftertaste and cool in potency. It is an eye and hair tonic. It pacifies pitta and vata, and is useful in management of cardiac ailments, hoarseness of voice, recovery from inflammation and wounds. Apoptotic
Anti-proliferative/Anti-growth
Anti-oxidant
Anti-metastatic/Anti-invasive
Ashwagandha Ashwagandha is astringent and bitter, hot in potency, and pacifies Vata and Kapha. It is alexipharmic, helpful in management of emaciation, and enhances complexion, potency and strength. It is helpful in management of inflammation and is a reproductive tonic. Apoptotic
Anti-proliferative/Anti-growth
Anti-oxidant
Anti-metastatic/Anti-invasive
Kumari Kumari is cool in potency, bitter in taste and pacifies Kapha and Pitta. It is alexipharmic, pacifies cough, dyspnea, skin diseases, burns, and wounds. It is helpful in the management of menstrual disorders and liver diseases. Apoptotic
Anti-proliferative/Anti-growth
Anti-oxidant
Anti-inflammatory
Gotu Kola Mandukaparni is astringent, sweet, cooling in potency, laxative, and light to digest. It enhances higher mental functions and memory. It improves voice and is helpful in management of skin diseases, diabetes, cough, poisoning, inflammation, and fever. Apoptotic
Anti-proliferative/Anti-growth
Anti-oxidant
DNA/RNA Degeneration
Guduchi Guduchi is bitter, astringent and hot in potency. It is heavy to digest and pacifies all the three Doshas. It is helpful in management of fevers, anemia, rheumatoid arthritis, vomiting, diabetes, and skin diseases Apoptotic
Anti-proliferative/Anti-growth
Anti-oxidant
Immunomodulatory

References:

Yashtimadhu (Glycyrrhiza glabra – licorice): Bhavaprakasha Nighantu, Haritakyadi Varga, 128–129; Raja Nighantu, Pippalyadi Varga, 144-145.

Ashwagandha (Withania somnifera): Dhanvanthri Nighantu, Guduchyadi Varga, 302–303, Madanapala Nighantu, Abhayadi Varga, 173-174.

Kumari (Aloe vera): Rajanighantu, Parpatadi Varga, 47–49, Bhavaprakasha Nighantu, Guduchyadi Varga, 196-197.

Gotu Kola (Centella asiatica): Bhavaprakasha Nighantu, Guduchyadi Varga, 236-237.

Guduchi (Tinospora cordifolia): Dhanvanthri Nighantu, Guduchyadi Varga, 5-7.

a

Top 4 pharmacologic actions are listed.