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. 2024 Jan 24;15:1350187. doi: 10.3389/fphar.2024.1350187

FIGURE 7.

FIGURE 7

The roles of HIF-1ɑ in vascular remodeling of OS cells. Annotation: HIF-1α-induced signal pathway regulates the vascular remodeling process of OS tissue and improves the anoxic environment of OS cells. At the same time, the vascular remodeling process will undoubtedly increase the risk of metastasis of OS cells.