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. 2024 Jan 24;15:1288362. doi: 10.3389/fphar.2024.1288362

FIGURE 3.

FIGURE 3

Hemorrhagic events and thrombocytopenia with HER2 inhibitors. (A) Mulberry map of clinical characteristics of patients with hemorrhagic events. Data were collected from regimen, age, sex, outcome (OUTC_COD), SOC types (soc_name), and preferred terms types (pt_name). Unknown indicates those not explicitly stated in the factor. (B, C) Heat map visualization of frequency distribution and reporting rates distribution of hemorrhagic events. (D, E) Wayne Map visualizes the overlapping relationship between haemorrhage and thrombocytopenia in patients receiving HER2 inhibitor therapy. (F) Chi-Square Test compares differences in Hemorrhagic events between TDM-1 and other HER2 inhibitors in patients reporting the presence of thrombocytopenia.