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. 2024 Jan 24;12:1302024. doi: 10.3389/fpubh.2024.1302024

Table 2.

Incidence rate ratio over a 12-year period for erectile dysfunction using multivariable models.

Factor All men RR (95% CI) p-value HIV-positive
RR (95% CI)
p-value HIV-negative
RR (95% CI)
p-value
HIV-positive vs. HIV-negative 1.41 (1.14–1.75) 0.002
Age (5 years) 1.19 (1.09–1.29) <0.001 1.21 (1.08–1.36) 0.001 1.15 (1.02–1.30) 0.024
Race and ethnicity
Black vs. white 1.00 (0.75–1.34) 0.983 1.14 (0.8–1.62) 0.475 0.88 (0.48–1.61) 0.689
Hispanic vs. white 1.20 (0.84–1.70) 0.321 1.57 (1.04–2.37) 0.032 0.59 (0.23–1.52) 0.272
BMI (1 unit) 1.00 (0.95–1.05) 0.933 1.02 (0.96–1.08) 0.494 0.97 (0.89–1.05) 0.427
Waist girth (10 cm) 1.07 (0.90–1.27) 0.437 0.99 (0.8–1.23) 0.922 1.19 (0.89–1.60) 0.241
Current diabetes (yes vs. no) 1.39 (1.10–1.75) 0.005 1.49 (1.11–1.98) 0.007 1.24 (0.83–1.86) 0.284
Current hypertension (yes vs. no) 1.22 (0.97–1.53) 0.084 1.10 (0.80–1.5) 0.555 1.28 (0.90–1.81) 0.172
Cumulative cigarette smoking pack-years (10 years) 1.33 (1.07–1.65) 0.009 1.25 (0.87–1.81) 0.228 1.44 (1.04–2.00) 0.027
Cumulative stimulant use years (10 years) 1.03 (0.98–1.07) 0.257 1.03 (0.99–1.07) 0.145 0.99 (0.83–1.19) 0.942
Cumulative antidepressant use years (10 years) 1.51 (1.20–1.90) <0.001 1.62 (1.19–2.21) 0.002 1.37 (0.95–1.99) 0.094
Cumulative alcohol drinking years (10 years) 1.00 (0.99–1.01) 0.961 0.99 (0.97–1.01) 0.514 1.00 (0.99–1.02) 0.70
Cumulative testosterone use years (10 years) 0.73 (0.42–1.27) 0.269 0.74 (0.39–1.41) 0.365 0.86 (0.29–2.54) 0.788
Cumulative sexual-enhancing drug use years (10 years) 0.79 (0.59–1.06) 0.123 0.73 (0.48–1.13) 0.158 0.87 (0.57–1.32) 0.503
Cumulative HAART use years (10 years) 1.36 (0.71–2.60) 0.35
HIV RNA ≥200 vs. <200 copies/ml 0.88 (0.65–1.18) 0.39
% CD4-positive cells (10%) 0.99 (0.84–1.17) 0.943

BMI, body mass index; HAART, highly active antiretroviral therapy; HIV, human immunodeficiency virus; RR, rate ratio. Bold type highlights statistical significance at p < 0.05.