Differentiated human brown adipocytes (hBAs) from AgeX-NP88 cell line improve glucose and insulin tolerance in NSG mice
(A–C) Weekly body weight (A), fat mass (B), and lean mass (C), 16-week post-transplant. (n = 9–10 per group).
(D) GTT AUC data at 16-week post-transplant (n = 9–10 per group; ∗∗p < 0.01 vs. Sham 16-week post-transplant; two-tailed t test).
(E) ITT AUC data at 16-week post-transplant (n = 9–10 per group).
(F) Plasma insulin levels at 20 weeks post-transplantation after 12-h fast (ng/mL) (n = 6–9 per group; ∗p < 0.05 vs. Sham, two-tailed t test). All data are represented as mean ± SEM.