FIG. 3.

Lung yeast burdens in young adult and aged mice after intratracheal instillation of C. neoformans. Young adult and aged AB6F₁ female mice received 10⁶ strain 184 yeast cells intratracheally. Mice were killed at 1, 2, 4, and 8 weeks of infection, and yeast cells were enumerated. Data are the means ± standard deviations (n = 5 mice/group except for 8 weeks, where n = 4 for young adult mice and n = 3 for aged mice). There were no significant differences between the two groups (Student’s t test, P < 0.05).