Supplemental Fig. 2.

In vivo mouse and blood measurements. A) Percentage chimerism of donor bone marrow measured by qPCR analysis of Ldlr expression in blood samples of Acod1^+/+ → Ldlr^−/− (filled) and Acod1^−/− → Ldlr^−/− (checkered) mice (n = 22/23 for Acod1^+/+ → Ldlr^−/− /Acod1^−/− → Ldlr^−/−). B) Mouse weight over the entire in vivo experiment starting from 1 week before BMT in Acod1^+/+ → Ldlr^−/− (black dots) and Acod1^−/− → Ldlr^−/− (white dots) mice (n = 22/23; dotted line is day of BMT). C) Cholesterol and D) triglyceride levels in blood plasma of mice at weeks 0, 5 and 8 of HFD (n = 22/23). E)In vivo blood cell subset composition per mL of blood at weeks 0, 5 and 8 of HFD (n = 22/23). Data points display individual mice and error bars show SD. BMT = Bone Marrow transplantation; HFD = High Fat Diet.