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. 2023 Aug 6;30(2):e14379. doi: 10.1111/cns.14379

FIGURE 4.

FIGURE 4

Both BTN and NEM decreased CCH‐induced hippocampal CA1 neuronal loss, preserved the BDNF expression, and prevented GABAAR subunit imbalance in CCH brains. Brain slices were subjected to Nissl staining and imaging. (A) Cell counting of the CA1 neurons was performed. (B) Western blotting and semi‐quantification of BDNF levels. (C) Western blotting and semi‐quantification of GABAAR α1 levels. (D) Western blotting and semi‐quantification of GABAAR α5 levels. BTN, bumetanide; CCH, Chronic cerebral hypoxia; NEM, N‐ethylmaleimide; PS‐low, sub‐anesthetic dose of combined propofol and sevoflurane. Data are mean ± SD. *p < 0.05 versus Sham; # p < 0.05 versus CCH.