FIG. 1.

Course of chlamydial genital disease in mice preinfected by various routes. Female BALB/c mice were infected with MoPn by the indicated routes and challenged i.v. 70 days later. The course of the infection was monitored by periodic (every 3 days) cervicovaginal swabbing of individual animals. Chlamydia was isolated from the swabs in tissue culture according to standard methods, and inclusions were visualized and enumerated by immunofluorescence (32, 34). Experiments were repeated two times to obtain data for 10 or 12 animals per group.