Table 1. Comparison of EC specific genes in different cell types.

Top 50 marker genes of tissuespecific EC populations from Table S2 in Kaluck et al¹¹ compared to the top 50 mRNAs expressed in skin wound ECs from GSE142471. mRNAs shared with skin wound ECs in each tissue are highlighted in yellow.

Data from Kalucka et al., 2020 Table S2														Data from Wasko et al. Table l Top 50 upregulate d genes in wounded ECs
Top-50 marker genes of tissue- specific EC phenotypes
Brain-largeartery	Brain-capillary	Brain-largevein	Testis-largeartery	Testis-capillary	Liver-Largeartery	Liver-capillary	Liver-proliferating	Lung-artery	Lung-capillary 1	Lunc-capillary 2	Colon-artery	Colon-capillary 1	Colon-capillary 2	Skin wound EC
Mgp	Cxcl12	Tmsb10	Edn1	Car4	Sdc1	Dnase1l3	Stmn1	Mgp	Car4	Gpihbp1	Clu	Car4	Esm1	Cst3
Cytl1	Spock2	Vcam1	Ifi27l2a	Ptn	Clu	Clec4g	Hmgb2	Tm4sf1	Igfbp7	Sema3c	Gja4	Rgcc	Plpp3	Scarb1
Fbln5	Gm9946	Slc38a5	Sox17	Slco1a4	Ehd4	Stab2	H2afz	Cxcl12	Emp2	Gm12216	Fbln5	Plpp1	Nrp1	Lrat
Clu	Lrrn3	Icam1	Gadd45g	Bsg	Cyp1a1	Ctsl	Cdkn1a	Plat	Pmp22	Stmn1	Glul	Aplnr	Mef2c	Pltp
Eln	Gstm7	Tmem252	Amd1	Gpcpd1	Plac8	Bmp2	Top2a	Plac8	Fibin	Sox17	Azin1	Ramp3	Cd24a	Bcam
Bgn	Palm	Lcn2	Ssu2	Slc3a2	Col8a1	Maf	Cdk1	Gja4	AW112010	Ier3	Igfbp4	Col4a1	Ehd4	S100a11
Igfbp4	Tbx3	Vwf	Ptprr	Ier3	Lrg1	Gatm	Cks2	Mecom	Cyp4b1	Plvap	Stmn2	Sparc	Tmem176a	Ly6c1
Cfh	Prdm16	Ctsc	Crip1	Ephb1	Mgp	Kdr	Birc5	Igfbp4	Ptp4a3	Socs3	S100a6	Nkx2−3	Fam167b	Apoe
Lmcd1	Rasgrp2	Tgm2	Ptma	Caskin2	Mecom	Mt1	Tuba1b	Atp13a3	Sept4	Wfdc1	Edn1	Hspg2	Rbp7	Rasa4
Bpgm	Cd83	Ackr1	S100a4	Tmem201	Cd200	Plpp3	Tk1	Apoe	Ednrb	Aplnr	Sox17	AW112010	Col13a1	Pfn1
Cmip	Pik3ip1	Apod	Wfdc1	Kazn	Fbln2	Cyp4b1	Hmgn2	Gja5	Cd34	Sgk1	Sema3g	Mgll	Oaz2	Slc30a1
Htra1	Pmaip1	Apoe	Cav1	Cspp1	Hspb1	Gpr182	Lgals1	Fxyd5	Prx	H2-Ab1	Ace	Sparcl1	Tmem176b	Lgals1
Sat1	Tnfrsf21	Nfkbia	Ier2	Usp32	AU021092	Mrc1	Cks1b	Tsc22d1	Chst1	Cadm1	Cst3	Fmo2	Smco4	Cxcl2
Bmx	Prkcb	Hs3st1	Jun	Setdb1	Ly6c1	Fam167b	Nucks1	Edn1	Tbx3	Casc4	Tsc22d1	Trp53i11	Ces2e	Cxx1a
Reck	Plekhh2	Ptn	Alox12	Zdhhc9	Cyr61	Fcgr2b	Pcna	Efnb2	Clu	Btg2	Tspan8	Col15a1	Vwa1	Marcksl1
Emp3	Gpr160	Ch25h	Btg2	Mcf2	Cd63	Adam23	H2afx	Sparcl1	Nrp1	Sparc	Slc6a6	Car8	Jam3	Serf2
Vim	Rftn2	Fth1	Lmna	Tiam1	Adgrg6	Oit3	Cdca8	Htra1	Kdr	Kit	Fbln2	Lamb1	Plscr2	Thy1
S100a11	Cnnm2	Ptgs2	Tgfb2	Aars2	Plvap	Cldn5	Spc24	Fbln2	Ly6c1	Hilpda	Tm4sf1	Sgk1	Kdr	C1qtnf9
Timp2	Krt222	Cxcl1	Klf2	Ndufaf1	Gja5	Apoe	Lockd	Hey1	Bcam	Tubb2a	Heg1	Enpp6	Thbd	Gm694
Ptgis	Helz	Net1	Stmn1	Mamstr	Crip1	Lgmn	Smc4	Fam3c	Tmcc2	Lpl	Gja5	Ivns1abp	Hspb1	Col18a1
Fhl1	Nanos1	Itih5	Cdkn1c	Nol4l	Cst3	Stab1	Cdkn2c	Sulf1	Tppp3	Sox11	Sat1	Jun	Pltp	Cxcl12
Ccnd2	Naa30	Rgs16	Chd3	Mfsd12	Npr3	Clec1b	Hjurp	Sema3g	Rgs12	Plk2	Gadd45g	Sox4	Ncoa7	Ndrg1
Cp	Napg	Rnase4	Klf4	Alg6	Sncg	Hpgd	Smc2	Id1	Phlda3	Jund	Mast4	Dusp6	Flt1	Gng5
Emp1	Ric1	Mt1	Eef1a1	Atg4a	Ednrb	Cd300lg	Tyms	Mgst1	Hspb1	Atp1a1	Hey1	Mcam	Slc16a1	Lgals7
Id2	Nt5dc2	Csf1	Cdk19	Sdad1	Ly6e	Aass	Tubb6	Heg1	Apln	H2-Q6	Plat	Apold1	Gm13889	Pecam1
Rhob	Vangl2	Serpinb9	Hspa1a	Tyw5	Mgst1	Akr1b8	Racgap1	Efna1	Enho	Ncald	Fn1	Ankrd37	Plscr1	Grem1
Tm4sf1	2310040G24Rik	Rbp1	Co18a1	Hspb6	Cd34	Tfpi	Lmnb1	Bmx	Pcdh1	Ccr12	Ssu2	Ednrb	Cd200	Fkbp1a
Fn1	Htatip2	Gm9844	Zfp36	0610010F05Rik	Nrg1	Col13a1	Nrm	Sat1	Nhlrc2	Npr3	Mecom	Rapgef4	Exoc3l2	Krt5
Emp2	Utp14b	Mt2	Rsad2	Galc	Vegfc	Mt2	Fen1	Crip1	Ly6a	Ier2	Eps8l2	Thbs1	Lrrc3b	Fam167b
Pam	Rbfa	Lrg1	Bmp2	Pign	Tm4sf1	Dab2	Fbxo5	Cdh13	Kitl	Adrb1	ssu2	Fos	Ptp4a3	Rhoc
Cd82	Adck2	Nr2f2	Hist1h1c	Gm17619	Ldb2	Lpar6	Cdc20	Mmrn2	Pllp	Car2	Syt15	Itga6	Itm2a	Col4a1
Jag1	Eif2ak4	Gbp4	Neb1	Zcchc10	Ier2	Clec14a	Mcm5	Ccnd2	Cldn5	Rdx	Hspala	Chrm2	Pcdh17	Fos
Spint2	Med27	Jun	Akap13	Fbxw4	Efna1	Mertk	Cenpa	Slc6a6	Tmem176a	Nckap5	8430408G22Rik	Apln	Tnfaip2	Tmsb4x
Irf6	2700046A07Rik	Il1r1	Med1	Gba2	Ddit4	Manf	Gmfg	Rps28	Rasgrp2	H2-Eb1	Crip1	Rad51ap1	Rsad2	Myct1
Kcnn4	Pias3	Tmem176b	Cit	Klhl17	Dusp1	Slc40a1	Ccdc34	Rbp7	Mgll	Junb	Dusp1	Selenbp1	Id3	Prelid1
Atp2a3	Fam136a	Foxf1	Dbndd2	Mms19	Syt15	Chst15	Ncapd2	Nrarp	Tbx2	Plcb1	40787	F2r13	Crim1	Rasd1
Ace	2610301B20Rik	Cpe	2810403A07Rik	Marf1	Fbln5	Ftl1	Tcf19	8430408G22Rik	Aard	Ifi47	Ybx1	Gbp2	Actg1	Col4a2
Nuak1	A630072M18Rik	Zfp36l2	Ccnl1	Zfp335	Abcg2	Sparc	Rfc3	Camk2d	Rprml	Car14	S100a4	Iigp1	Gas7	Ctla2a
Gja4	Nup37	Serpinb6b	Rnf152	Dgkq	Gm13889	Cyp26b1Myo10	Cxcl10	Cdc42ep3	Tspan8	Tmem221	Car7	Hes1	Serpinb1a	mt-Nd5
Lmo1	Dnase2a	Dusp23	Ppp1r15a	Gxylt1	Fxyd5	Myo10	Ltc4s	Psen2	Stmn2	Ada mts1	Bmx	Hrct1	Prdm1	Csrp2
Sdc1	Zfp788	Polk	Tmem243	Cwc27	Utrn	Mylip	Hsp90aa1	Gata6	Dhrs3	Ldb2	Klf4	Arrdc3	Efhd1	Hspb1
Synpo	Slc43a2	Cd14	Smarcd1	Fam212b	Lmo7	Adgrf5	Lig1	Rgs3	Plaur	Pcdh17	Htra1	Chchd10	Penk	Cf11
Edn1	Usp43	Dnm3	Il20rb	Traf3ip1	Fos	Cpne2	Usp1	Tmem158	Ccdc184	Irf1	Jag1	Btg2	Abcg2	RP23-354H24.9
Mmrn2	Cbx8	Il6st	Cd36	Fbxl18	8430408G22Rik	SlcB9a8	Bok	Mast4	Icam1	Cdc42ep4	Pcsk5	H1f0	Actb	Sectm1a
Tspan7	Nhlrc3	Car14	Adarb1	Gm20045	Ltbp4	Ets2	Raph1	Fmo2	Cd24a	Pxdc1	Lima1	Bpgm	Akr1c14	Tgfbi
Phlda3	Clk2	Gm5127	Klhdc8b		NrarP	Plet1os	Pold2	Fads3	Slc48a1	Vgll4	Lamb2	Xpc	Nr5a2	Slc3a2
Arl15	Angptl4	Wnt5a	RasgrP3		Cmklr1	Itpkb	Nav2	Mcam	Grina	Ankrd44	Efnb2	Col4a3	B2m	Myeov2
Dkk2	BC0B70B4	Sema6a	Tmbim1		Cd9	Hsp90b1	Rpa2	Itga6	Scn7a	Cd1d1	Atp13a3	Ankrd44	Tnfrsf11b	Bsg
Fstl1	Naa16	Flrt2	Rsrp1		Ehd2	Cd84	Ezh2	Lgals3bp	Serpine1	Rapgef4	Mal	Hic1	Rcan2	Sectm1b
H2-Q6	B4galt7	Car2	Ppp1r15a		Trim47	Itga9	Rrm1	Ebf1	Phlda1	Tubb2b	Adamts1	Serpine1	Cdc14a	Hist1h2bc