Table 2.
Univariate and multivariate analyses of survival in patients with CRC (Cox proportional hazards regression model)
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | |
| Age | 1.315 | 0.906–1.909 | 0.149 | |||
| >55 VS ≤ 55 | ||||||
| Gender | 0.885 | 0.670–1.412 | 0.973 | |||
| Female VS male | ||||||
| Tumor site | 1.191 | 0.786–1.806 | 0.409 | |||
| Colon VS Rectum | ||||||
| Tumor size | 1.419 | 0.922–2.184 | 0.111 | |||
| >3.5 cm VS ≤ 3.5 cm | ||||||
| Differentiation degree | 4.153 | 2.501–6.896 | 0.000 | 2.406 | 1.635–3.542 | 0.001 |
| Poor VS High/median | ||||||
| Vascular invasion | 1.333 | 0.872–1.811 | 0.203 | |||
| Positive VS negative | ||||||
| Nerve invasion | 1.020 | 0.777–1.295 | 0.265 | |||
| Positive VS negative | ||||||
| TNM stage | 1.972 | 1.300–2.991 | 0.001 | 2.442 | 1.291–4.620 | 0.006 |
| I/II VS III/IV | ||||||
| ZCCHC4 expression | 2.503 | 1.71–3.663 | 0.000 | 2.352 | 1.467–3.772 | 0.000 |
| Decreased VS Non-decreased | ||||||