Fig 3.

Absolute number of APCs in the skin of C. auris- and C. albicans-infected mice groups. Mice were euthanized after 3 and 14 days post-infection to determine the APCs in the skin tissue. (A) Flow gating strategy of antigen-presenting cells gated from CD11c+ MHC-II+ cells is shown here. Representative flow plots (B) and absolute number of (C) CD11b+ CD207− cells (CD11b+ dendritic cells), (D) CD11b+ CD207+ cells (Langerhans cells), and (E) CD11b− CD207+ cells (CD103+ dendritic cells) in C. auris- or C. albicans-infected mice skin tissue after 3 and 14 days post-infection are shown. Seven to ten mice were used for each group and data represented were mean ±  standard error of the mean for each group. statistical significance was calculated using Mann-Whitney U test. *P ≤ 0.05 was considered as significant. APC, antigen-presenting cell.