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Cytotoxicity against the MCF-7 Human Breast Cancer Cell Line
| Compound | IC50 (μM) SRB assay MCF-7a |
|---|---|
| OXi8006 b | 0.048 ± 0.01 |
| 5a | >5 |
| 5b | 2.7 ± 0.2 |
| 5c | 0.47 ± 0.02 |
| 5d | >5 |
| 5e | 3.7 ± 0.07 |
| 5f | 1.7 ± 0.2 |
| 5g | 4.8 ± 0.3 |
| 5h | 0.78 ± 0.2 |
| 5i | >5 |
| 5j | >5 |
| 5k | 0.84 ± 0.09 |
| 5l | 3.2 ± 1.0 |
| 5m | 1.6 ± 0.4 |
| 5n | 2.2 ± 0.5 |
Average of n ≥ 3 independent determinations
See ref16 for additional OXi8006 data
