. Author manuscript; available in PMC: 2024 Sep 7.

Published in final edited form as: Bioorg Med Chem. 2023 Jun 29;92:117400. doi: 10.1016/j.bmc.2023.117400

Table 3.

Cytotoxicity Evaluation Against the MDA-MB-231 Human Breast Cancer and Pancreatic Cancer PANC-1 Cell Lines in Comparison with the MCF-7 Data

Compound	IC₅₀ (μM) SRB assay MCF-7^a	IC₅₀ (μM) SRB assay MDA-MB-231^a	IC₅₀ (μM) SRB assay PANC-1^a
OXi8006	0.048 ± 0.01	0.044 ± 0.008	ND^b
5c	0.47 ± 0.02	1.9 ± 0.1	0.43 ± 0.1
5h	0.78 ± 0.2	3.0 ± 1.0	0.44 ± 0.01
5k	0.84 ± 0.09	2.2 ± 0.2	1.1 ± 0.5

Average of n ≥ 3 independent determinations

ND: not determined