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. 2024 Feb 8;73(1):1–32. doi: 10.15585/mmwr.rr7301a1

FIGURE 3.

Figure illustrates the traditional and reverse sequence algorithms that can be applied to screening for syphilis with serologic tests.

Algorithms that can be applied to screening for syphilis with serologic tests — CDC laboratory recommendations for syphilis testing in the United States, 2024

Abbreviations: CIA = chemiluminescence immunoassay; EIA = enzyme immunoassay; RPR = rapid plasma regain; TPPA = Treponoma pallidum particle agglutination; VDRL = Venereal Disease Research Laboratory.