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. 2024 Feb 6;8(2):e23.00206. doi: 10.5435/JAAOSGlobal-D-23-00206

Table 2.

Charlson Comorbidity Index for the Control, Tetrahydrocannabinol-Only, and Tetrahydrocannabinol-Opioid–Positive Groups

Factor Control
n = 252
Multidrug
N = 47
THC Only
n = 54
P
Charlson Comorbidity Index
 Myocardial Infarction 8 (3.17%) 3 (6.38%) 1 (1.85%) 0.43
 Congestive heart failure 3 (1.19%) 0 2 (3.7%) 0.25
 Peripheral vascular disease 14 (5.56%) 2 (4.26%) 1 (1.85%) 0.50
 Cerebrovascular accident 4 (1.59%) 1 (2.13%) 0 0.61
 Dementia 10 (3.97%) 4 (8.51%) 1 (1.85%) 0.23
 Chronic obstructive pulmonary disease 17 (6.75%) 8 (17.02%) 4 (7.41%) 0.06
 Connective tissue disorder 4 (1.59%) 0 0 0.44
 Peptic ulcer 89 (35.32%) 21 (44.68%) 18 (33.33%) 0.42
 Liver disease 2 (0.79%) 0 0 0.67
 Diabetes mellitus 48 (19.05%) 8 (17.02%) 7 (12.96%) 0.56
 Hemiplegia 1 (0.40%) 0 0 0.82
 Chronic kidney disease 4 (1.59%) 2 (4.26%) 0 0.25
 Solid tumor 1 (0.40%) 4 (8.51%) 2 (3.7%) <0.001
 Leukemia 0 0 0
 Lymphoma 0 0 0
 AIDS 0 0 0

THC = tetrahydrocannabinol