Table 1.
Characteristics of included systematic review and meta-analysis studies
| s.no. | Author and years | Publication period of primary studies | Included studies | Search strategies | Sample size | Risk of bias | The primary outcome of the review | Reported prevalence (%) | Reported factors |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Assemie et al. 202015 | 2005–2019 | 18 studies (8 Cross-sectional and 10 cohort studies) | PubMed, Cochrane Library, ScienceDirect, Web of Science, and Google Scholar | 10 495 | Clear quality appraisal of studies reported using NOS | Prevalence of neonatal sepsis | 45% (95% CI: 35, 55; I2 =99:3%) | None |
| 2. | Bayih et al., 202118 | 2005–2019 | 27 studies (23 cross-sectional, 3 case-control 1 cohort study designees) | Google Scholar, HINARI, SCOPUS, and PubMed | 36 016 | Clear quality appraisal of studies reported using NOS | The burden of neonatal sepsis and its association with antenatal UTI and intrapartum fever | 40.25% [95% CI:34.00%, 46.50%; I2 =99.2%] | Antenatal urinary tract infection OR=3.55 (95% CI: 2.04, 5.06), having intrapartum fever OR=3.63 (95% CI: 1.64, 5.62) |
| 3. | Belachew and Tewabe, 202021 | 2014–2018 | 8 studies (7 cross-sectional and 1 cohort study designs) | PubMed, CINHAL, EMBASE, Google Scholar, Web of Science, Cochrane Library databases, and African Health Science library | 9032 | Clear quality appraisal of studies reported using NOS | Prevalence of neonatal sepsis and its association with birth weight and gestational age | 49.98% (CI: 36.06, 63.90) | Low birth weight OR=1.42 (95% CI, 1.07, 1.88) and preterm OR=3.36 (95% CI: 2.50, 4.54) |
| 4. | Seyoum et al., 202320 | Before 3/31/2022 | 15 studies (8 case-control, 7 cross-sectional) | PubMed/Medline, Hinari, and Google Scholar | 4895 | Clear quality appraisal of studies reported using NOS | Determinants of neonatal sepsis | Na | Prolonged rupture of membrane (OR:4.03, 95% CI:1.88–8.60), low first-minute APGAR score (OR: 3.74, 95% CI:1.29–10.81), low fifth-minute APGAR score (OR:2.72, 95% CI:2.02–3.67), and delayed initiation of breastfeeding (OR: 3.41, 95% CI:2.18–5.36) |
| 5. | Desta m et al. 202119 | 2014–2020 | 33 studies (17 cross-sectional, 9 case-control, 7 cohort) 9 studies reported neonatal sepsis (6 cross-sectional, 3 case-control) |
PubMed, Web of Science, SCOPUS, CINAHL, Google Scholar, African Journals Online databases, and Science Direct. | 20 109 2601 | Clear quality appraisal of studies reported using NOS | effect of preterm birth on adverse perinatal and neonatal outcomes | NA | Preterm [OR=2.33 (95% CI: 1.15, 4.71)] |
NA, not applicable; OR, odds ratio.