Fig. 2. Mito-transfer modulates the expression of CD4⁺ T cell senescence-associated genes.

A) Heatmap of proteins related to T cell aging/senescence from CD4+ T cells from old mice with and without mito-transfer (4h). B) Pathway & Process Enrichment (PPE) analysis & Protein-Protein Interaction (PPI) networks, and C) Molecular Complex Detection (MCODE) clusters identified as significantly downregulated in CD4⁺ T cells from old mice after mito-transfer. Bioinformatic Analysis was performed using the MetaScape analysis tool.