Table 1. Neutralization titers against 18 pseudotyped virus.
| Rabbit antiserum | Phylogroup | Neutralization titers against VSVp (IC75) |
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| I |
II |
Unclassified |
|||||||||||||||||
| RABV | GBLV | ABLV | KHUV | BBLV | EBLV-2 | ARAV | KBLV | EBLV-1 | DUVV | IRKV | TWBLV | MOKV | SHIBV | LBV | WCBV | LLEBV | IKOV | ||
| RABV-G | I | 2,187 | 726 | 2,475 | 444 | 951 | 1,348 | 468 | 450 | 89 | 1,211 | 1,989 | 135 | <10 | <10 | <10 | <10 | <10 | <10 |
| GBLV-G | I | 10,399 | 23,970 | 40,105 | 11,897 | 22,308 | 4,739 | 5,312 | 7,632 | 874 | 20 | 3,662 | 8,174 | 49 | 520 | 30 | 213 | <10 | <10 |
| ABLV-G | I | 7,671 | 37,844 | 81,190 | 19,883 | 12,229 | 8,733 | 7,664 | 9,583 | 2,229 | 7,026 | 10,193 | 456 | 760 | 792 | 470 | <10 | <10 | <10 |
| KHUV-G | I | 487 | 3,985 | 9,228 | 11,342 | 1,954 | 1,455 | 1,931 | 3,501 | 155 | 51 | 443 | 166 | 352 | 937 | 228 | <10 | <10 | <10 |
| BBLV-G | I | 4,489 | 24,544 | 37,041 | 16,180 | 32,422 | 11,573 | 11,660 | 12,695 | 3,026 | 15,360 | 11,753 | 7,289 | 93 | 191 | 330 | <10 | <10 | <10 |
| EBLV-2-G | I | 1,743 | 12,916 | 34,401 | 9,532 | 9,250 | 13,190 | 10,699 | 6,968 | 5,588 | 1,402 | 3,263 | 749 | 272 | 1,264 | 294 | 38 | <10 | <10 |
| ARAV-G | I | 5,052 | 9,050 | 16,112 | 5,086 | 6,592 | 3,763 | 15,416 | 4,985 | 2,014 | 4,187 | 9,732 | 5,531 | <10 | 26 | 14 | <10 | <10 | <10 |
| KBLV-G | I | 1,082 | 4,902 | 16,737 | 3,787 | 2,358 | 3,208 | 1,518 | 8,643 | 370 | 777 | 421 | 1,169 | <10 | <10 | 12 | <10 | <10 | <10 |
| EBLV-1-G | I | 970 | 2,524 | 5,805 | 4,365 | 3,410 | 3,088 | 2,266 | 3,563 | 4,012 | 2,145 | 5,894 | 1,191 | 688 | 950 | 412 | 27 | <10 | <10 |
| DUVV-G | I | 4,880 | 19,159 | 59,446 | 38,658 | 29,820 | 47,743 | 37,519 | 35,864 | 17,659 | 116,600 | 60,585 | 2,325 | 43 | 353 | 164 | <10 | <10 | <10 |
| IRKV-G | I | 1,363 | 1,288 | 2,705 | 1,559 | 1,278 | 1,338 | 733 | 1,149 | 620 | 1,583 | 7,878 | 756 | 53 | 10 | 167 | <10 | <10 | <10 |
| TWBLV-G | I | 5,886 | 14,278 | 20,533 | 5,981 | 10,028 | 6,499 | 5,640 | 9,130 | 1,821 | 5,301 | 6,321 | 44,684 | 104 | 92 | 87 | <10 | <10 | <10 |
| MOKV-G | II | 956 | 959 | 7,125 | 3,146 | 570 | 1,592 | 529 | 1,657 | 30 | 32 | 74 | 299 | 201,967 | 4,311 | 2,924 | 67 | <10 | 24 |
| SHIBV-G | II | 14,254 | 43,130 | 64,102 | 43,625 | 12,745 | 3,711 | 9,606 | 10,610 | 888 | 604 | 11,297 | 911 | 36,372 | 512,586 | 73,811 | <10 | <10 | <10 |
| LBV-G | II | 166 | 553 | 1,491 | 278 | 223 | 123 | 33 | 272 | 20 | 29 | 195 | 63 | 154 | 4,697 | 5,103 | <10 | <10 | 42 |
| WCBV-G | Unclassified | 148 | 1,559 | 3,716 | 2,067 | 2,437 | 2,910 | 86 | 617 | 359 | 40 | 177 | 48 | 70 | 45 | 138 | 8,116 | <10 | 45 |
| LLEBV-G | Unclassified | <10 | <10 | <10 | 23 | 56 | 295 | <10 | <10 | <10 | <10 | <10 | <10 | <10 | <10 | <10 | <10 | 39,418 | 2,867 |
| IKOV-G | Unclassified | <10 | <10 | <10 | <10 | <10 | 31 | <10 | <10 | <10 | <10 | <10 | <10 | <10 | 327 | 12 | <10 | 17 | 22,752 |
| Rabipur-1 | I (vaccine) | 21,066 | 22,289 | 36,116 | 10,046 | 23,967 | 15,403 | 14,030 | 11,803 | 5,624 | 16,880 | 31,772 | 8,860 | <10 | 78 | 17 | <10 | <10 | <10 |
| Rabipur-2 | I (vaccine) | 7,887 | 11,055 | 20,947 | 3,193 | 7,848 | 8,059 | 5,446 | 4,386 | 2,067 | 8,791 | 11,494 | 2,120 | 44 | 158 | 72 | <10 | <10 | <10 |
| KMB-1 | I (vaccine) | 19,532 | 13,531 | 18,577 | 7,089 | 17,253 | 10,750 | 7,458 | 7,471 | 2,578 | 16,155 | 11,008 | 7,247 | <10 | <10 | <10 | <10 | <10 | <10 |
| KMB-2 | I (vaccine) | 9,004 | 3,295 | 7,359 | 2,143 | 2,821 | 1,854 | 1,052 | 766 | 146 | 1,223 | 1,456 | 1,965 | <10 | <10 | <10 | <10 | <10 | <10 |
The abbreviations for the 18 pseudotyped viruses (VSVp) and antisera against each lyssavirus glycoprotein (-G) are listed below: RABV, Rabies lyssavirus; GBLV, Gannoruwa bat lyssavirus; ABLV, Australian bat lyssavirus; KHUV, Khujand lyssavirus; BBLV, Bokeloh bat lyssavirus; EBLV-2, European bat lyssavirus 2; ARAV, Aravan lyssavirus; KBLV, Kotalahti bat lyssavirus; EBLV-1, European bat lyssavirus 1; DUVV, Duvenhage lyssavirus; IRKV, Irkut lyssavirus; TWBLV, Taiwan bat lyssavirus; MOKV, Mokola lyssavirus; SHIBV, Shimoni bat lyssavirus; LBV, Lagos bat lyssavirus; WCBV, West Caucasian bat lyssavirus; LLEBV, Lleida bat lyssavirus; IKOV, Ikoma lyssavirus. The sera of the rabbits immunized with human rabies vaccine (Rabipur) and animal rabies vaccine (KMB) were also used.