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. 2023 Dec 18;626(7998):435–442. doi: 10.1038/s41586-023-06953-1

Extended Data Fig. 1. Low affinity RFjoint-Inpainted binders for NPY and GCG using extended parametric designs.

Extended Data Fig. 1

(a) Left: Design model (colour spectrum + yellow) of the tightest GCG binder. Right: FP titration (n = 4) for the tightest GCG binder indicates ~ 231 nM binding affinity (b) Left: Design model (colour spectrum + dark green) of the tightest NPY binder. Right: FP titration (n = 4) for the tightest NPY binder indicates 3.5 µM binding affinity.