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. 2023 Dec 18;626(7998):435–442. doi: 10.1038/s41586-023-06953-1

Extended Data Fig. 2. Additional binders made using threading and redesign.

Extended Data Fig. 2

(a) Left: Design model (colour spectrum + dark blue) of the tightest GLP1 binder. Right: FP titration (n = 4) for the tightest GLP1 binder indicates 68.8 nM binding affinity (b) Left: Design model (colour spectrum + green) of the tightest GIP binder. Right: FP titration (n = 4) for the tightest GIP binder indicates 6.96 nM binding affinity.