Fig. 1.

Associations between adversities and risk of total CVD among 136,073 participants in the UKB. (A) Proportions of participants in each adversity group. (B) Crude incidence rate (per 1000 person-years) of total CVD in each adversity group. (C) Adjusted hazard ratios and their 95% CI of total cardiovascular diseases (CVD), which were derived from Cox proportional regression model with adjustment for age, sex, race/ethnicity, Townsend deprivation index, family history of heart disease, and stroke, and other types of adversity. Cumulative adversities denote adversities in both childhood and adulthood.