Fig. 3.

The effect of pitavastatin calcium treatment (4 mg/day; D0) for 180 days on baseline plasma concentrations of total lysolipids in the HDL2b (calculated as the sum of LPC, LPC(O), LPI, and LPE) (panel A) and in the HDL2a (panel B) subclsses from hypertriglyceridemic subjects. Data are expressed as means ± SEM (n = 12) in pmol of lysolipids/pmol PC. Percent change (%) was calculated relative to baseline values (D0). ∗∗∗P < 0.001; ∗∗0.001 < P < 0.01, and ∗0.01 < P < 0.05 versus D0. Density ranges: HDL2b = 1.063–1.091 g/ml; HDL2a = 1.091–1.110 g/ml. LPC, lysophosphatidylcholine; LPC(O), lysoalkylphosphatidylcholine; LPI, lysophosphatidylinositol; LPE, lysophosphatidylethanolamine.