Fig. 6.

Heat map of protein distribution patterns across HDL density subclasses in hypertriglyceridemic subjects. HDL subclasses are indicated at the top. The proteins identified by Scaffold peptide analysis are listed at left. The spectral counts (i.e., the total number of spectra identified for all peptides within a given protein) were determined for each protein in each fraction; data for D0 and D180 time points were combined given the minor differences in total proteome of HDL between them. The fraction that contained the highest peptide count for a given protein was normalized to 1 and all other values for that protein were scaled accordingly. The highest relative values are colored red and graduate to yellow for the lowest values (blue indicates that no peptides were found in any sample). Proteins were ordered in terms of preference from least dense to most dense based on the peak fraction.