Table 3.

Comparison of epidemiological data and pre-existing conditions, rupture status, and aneurysm multiplicity across the entire cohort and the matched sub-cohort, including tests for significant differences between cohorts

	Whole cohort (n = 186)			Matched cohort (n = 64)
	AcomA (n = 154)	BA (n = 32)	Statistical analysis	AcomA (n = 32)	BA (n = 32)	Statistical analysis
Gender	M = 69; F = 85	M = 7; F = 25	p = 0.008*	M = 7; F = 25	M = 7; F = 25	p = 1*
Age	53.9 years	56.8 years	p = 0.149**	55.2 years	56.8 years	p = 0.248**
Hypertension	108 (70.1%)	23 (71.9%)	p = 0.724*	25 (78%)	23 (71.9%)	p = 0.714*
Diabetes mellitus	13 (8.4%)	4 (12.4%)	p = 0.503***	2 (6.2%)	4 (12.4%)	p = 0.485***
Hyperlipidemia	21 (13.6%)	7 (21.9%)	p = 0.083***	6 (18.8%)	7 (21.9%)	p = 0.873***
Peripheral arterial disease	3 (2%)	2 (6.2%)	p = 0.187***	0 (0%)	2 (6.2%)	p = 0.238***
Heart disease	24 (15.6%)	4 (12.4%)	p = 0.531***	2 (6.2%)	4 (12.4%)	p = 0.361***
Ischaemic stroke	9 (5.8%)	1 (3.1%)	p = 0.489***	0 (0%)	1 (3.1%)	p = 0.492***
Thrombosis	6 (4%)	0 (0%)	p = 0.350***	1 (3.1%)	0 (0%)	p = 0.738***
Malignant tumor disease	5 (3.3%)	3 (9.4%)	p = 0.711***	1 (3.1%)	3 (9.4%)	p = 0.488***
Autoimmune disease	17 (11%)	0 (0%)	p = 0.042***	9 (28.1%)	0 (0%)	p = 0.508***
Obesity	50 (32.5%)	12 (37.5%)	p = 0.762*	1 (3.1%)	12 (37.5%)	p = 0.59*
Nicotine abuse	79 (51.3%)	16 (50%)	p = 0.689*	18 (56.3%)	16 (50%)	p = 0.748*
Alcohol abuse	21 (13.6%)	5 (15.6%)	p = 0.517*	1 (3.1%)	5 (15.6%)	p = 0.142***
Hormonal medication	0 (0%)	2 (6.3%)	p = 0.027***	0 (0%)	2 (6.3%)	p = 0.229***
Ruptured aneurysms	114 (74%)	15 (46.9%)	p = 0.005*	21 (65.6%)	15 (46.9%)	p = 0.206*
Multiple aneurysms	44 (28.6%)	16 (50%)	p = 0.012*	9 (28.1%)	16 (50%)	p = 0.127*
Aneurysm size (mean in cm)	5.7	5.7	0.928**	5.5	5.7	p = 0.397****

Significant results are highlighted in bold

AcomA anterior communicating artery aneurysm, BA basilar tip aneurysm

^*chi-square test, **Mann–Whitney U test, ***Fisher exact test, ****t-test