Table 6.

Multivariable Cox Regression for log2(NLR)

Outcome	Model 1		Model 2		Model 3
	Estimated hazard ratio (95% CI)	p value	Estimated hazard ratio (95% CI)	p value	Estimated hazard ratio (95% CI)	p value
Overall CTR-CVT	1.441 (1.069–1.942)	0.016*	1.464 (1.028–2.084)	0.034*	1.299 (0.814–2.073)	0.272

Model 1: Adjustment for age and sex; Model 2: Adjustment for age, sex, hypertension, dyslipidemia, diabetes mellitus, obesity, history of smoking, coronary artery disease (CAD), congestive heart failure, valvular heart disease, coronary artery bypass graft (CABG), peripheral and cerebral artery occlusive disease, previous myocardial infarction, percutaneous coronary intervention (PCI) or stroke and atrial fibrillation; Model 3: Adjustment for age, sex, hypertension, dyslipidemia, diabetes mellitus, obesity, history of smoking, coronary artery disease (CAD), congestive heart failure, valvular heart disease, coronary artery bypass graft (CABG), peripheral and cerebral artery occlusive disease, previous myocardial infarction, percutaneous coronary intervention (PCI) or stroke, atrial fibrillation and cancer entities

NLR neutrophil-to-lymphocyte ratio; CI confidence interval; CTR-CVT cancer therapy-related cardiovascular toxicity

*Statistically significant association between NLR and outcome