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. 2024 Jan 25;11:1322773. doi: 10.3389/fchem.2023.1322773

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Copyright © 2024 Metebi, Kauffman, Xu, Singh, Nayback, Fan, Johnson, Diemer, Grimm, Zamiara and Zinn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pb-214/Bi-214-TCMC-Trastuzumab treatment effectively inhibits colony formation in HER2+ SKOV3 ovarian cancer cells (A,B). (A) Representative images of three groups (n = 3) and (B) summary analyses of living cells showing the Pb-214/Bi-214 response in killing SKOV-3 cells in a clonogenic assay. ****, p < 0.0001 compared to untreated control.