Table 1.
Physicochemical evaluation of CIP- and LEV-loaded nanoparticles.
| Parameter | Formula | ||
|---|---|---|---|
| FCIP | FLEV | Plain NPs | |
| Size (nm) | 268.3 ± 4.15 | 271.1 ± 9.14 | 263.3 ± 2.76 |
| PDI | 0.03 ± 0.01 | 0.05 ± 0.02 | 0.03 ± 0.01 |
| ZP (mV) | − 8.88 ± 0.5 | − 8.67 ± 0.41 | − 8.67 ± 0.9 |
| EE% | 54.11 ± 2.66 | 28.14 ± 4.56 | – |
| AL% | 8.64 ± 0.42 | 5.09 ± 0.83 | – |
| Y% | 73.65 ± 12.68 | 64.88 ± 11.41 | 66.7 ± 12.94 |
CIP ciprofloxacin, LEV levofloxacin, FCIP CIP-loaded nanoparticles, FLEV LEV-loaded nanoparticles, plain NPs plain PCL nanoparticles, PDI polydispersity index, ZP zeta potential, EE% entrapment efficiency, AL% antibiotic loading, Y% yield.