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. 2023 Sep 25;95(2):125–133. doi: 10.1136/jnnp-2023-331864

Table 2.

Kaplan-Meier estimates of NEDA and freedom from clinical relapses, MRI events and CDW by year

Year Clinical relapse MRI event CDW NEDA
KM 95% CI KM 95% CI KM 95% CI KM 95% CI
1 95% 92% to 98% 99% 97% to 100% 98% 96% to 100% 92% 88% to 96%
2 92% 89% to 96% 97% 94% to 100% 96% 94% to 99% 87% 82% to 93%
3 91% 87% to 96% 94% 91% to 98% 95% 91% to 98% 83% 77% to 89%
5 87% 82% to 93% 88% 83% to 94% 91% 87% to 96% 73% 66% to 80%
10 86% 80% to 92% 79% 69% to 90% 87% 80% to 94% 65% 56% to 74%

CDW, confirmed disability worsening; KM, Kaplan-Meier estimate; NEDA, no evidence of disease activity.