Table 2.
Year | Clinical relapse | MRI event | CDW | NEDA | ||||
KM | 95% CI | KM | 95% CI | KM | 95% CI | KM | 95% CI | |
1 | 95% | 92% to 98% | 99% | 97% to 100% | 98% | 96% to 100% | 92% | 88% to 96% |
2 | 92% | 89% to 96% | 97% | 94% to 100% | 96% | 94% to 99% | 87% | 82% to 93% |
3 | 91% | 87% to 96% | 94% | 91% to 98% | 95% | 91% to 98% | 83% | 77% to 89% |
5 | 87% | 82% to 93% | 88% | 83% to 94% | 91% | 87% to 96% | 73% | 66% to 80% |
10 | 86% | 80% to 92% | 79% | 69% to 90% | 87% | 80% to 94% | 65% | 56% to 74% |
CDW, confirmed disability worsening; KM, Kaplan-Meier estimate; NEDA, no evidence of disease activity.